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Vaccinia Virus
New vaccinia virus study findings have been reported by scientists at University of London, Medical Department
July 30th, 2008
According to recent research from London, the United Kingdom, "The I kappa B kinase ( IKK) complex is a key regulator of signal transduction pathways leading to the induction of NF-kappa B-dependent gene expression and production of pro- inflammatory cytokines. It therefore represents a major target for the development of anti-inflammatory therapeutic drugs and may be targeted by pathogens seeking to diminish the host response to infection." "Previously, the vaccinia virus ( VACV) strain Western Reserve B14 protein was characterised as an intracellular virulence factor that alters the inflammatory response to infection by an unknown mechanism. Here we demonstrate that...
Source: Vaccine Weekly (2008-07-30)
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