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Vaccine Weekly

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Central Nervous System Infection



Study results from T. Couderc and colleagues in the area of central nervous system infection published



July 30th, 2008

"Chikungunya virus (CHIKV) is a re-emerging arbovirus responsible for a massive outbreak currently afflicting the Indian Ocean region and India. Infection from CHIKV typically induces a mild disease in humans, characterized by fever, myalgia, arthralgia, and rash," scientists in Paris, France report.

"Cases of severe CHIKV infection involving the central nervous system (CNS) have recently been described in neonates as well as in adults with underlying conditions. The pathophysiology of CHIKV infection and the basis for disease severity are unknown. To address these critical issues, we have developed an animal model of CHIKV infection. We show here that whereas wild type...


Source: Vaccine Weekly (2008-07-30)

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