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DNA Vaccines



Reports outline DNA vaccines research from University of Pennsylvania



August 6th, 2008

New research, 'Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques,' is the subject of a report. According to a study from the United States, "DNA vaccines are a promising technology. Historically, however, the ability of DNA vaccines to induce high response rates and strong immune responses, especially antibody responses, in non-human primates and human clinical trials has proven suboptimal."

"Here, we performed a pilot study in rhesus macaques to evaluate whether we could improve the immunogenicity of DNA vaccines through the use of adjuvant technology and improved delivery systems. The study consisted of four groups of...


Source: Vaccine Weekly (2008-08-06)

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