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Vaccine Weekly

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Cancer Vaccines



New findings from Auburn University, Medical Department in the area of cancer vaccines published



August 6th, 2008

According to a study from the United States, "Mammary cancer is among the most prevalent of canine tumors frequently resulting in death due to metastatic disease. Most tumors fail to raise an effective immune reaction making improving immune recognition a priority."

"Hybrid-cell fusion strategies have been employed to load dendritic cell populations with tumor cell antigens to stimulate immune recognition; however, recovery, heterogeneity and quality of primary cells from patients present enormous challenges. We employed allogeneic cell lines to develop an improved hybrid-cell fusion strategy and evaluated immune reactions in normal laboratory beagles. Such a strategy...


Source: Vaccine Weekly (2008-08-06)

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