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Vaccine Weekly

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Mycobacteria



Findings from University of Bergen provide new insights into mycobacteria



August 6th, 2008

According to recent research published in the journal Proteomics, "Tuberculosis is an ancient disease that remains a significant global health problem. Because many membrane and membrane-associated proteins of this pathogen represent potential targets for drugs, diagnostic probes or vaccine components, we have analysed Mycobacterium bovis, bacillus Calmette-Guerin (BCG) substrain Moreau, using Triton X-114 for extraction of lipophilic proteins, followed by identification with LC coupled MS/MS."

"We identified 351 different proteins in total, and 103 (29%) were predicted as integral membrane proteins with at least one predicted transmembrane region and another 84...


Source: Vaccine Weekly (2008-08-06)

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