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HIV/AIDS Vaccines
New research on HIV/AIDS vaccines from EpiVax summarized
August 6th, 2008
Investigators publish new data in the report 'Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV.' According to recent research published in the journal Vaccine, "Genetic polymorphisms in class I human leukocyte antigen molecules (HLA) have been shown to determine susceptibility to HIV infection as well as the rate of progression to AIDS. In particular, the HLA-B7 supertype has been shown to be associated with high viral loads and rapid progression to disease." "Using a multiplatform in silico/in vitro approach, we have prospectively identified 45 highly conserved, putative HLA-B7 restricted HIV CTL epitopes and...
Source: Vaccine Weekly (2008-08-06)
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