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HIV/AIDS Vaccines

Report summarizes HIV/AIDS vaccines study findings from National Institutes of Health

Published in Vaccine Weekly, August 6th, 2008

New research, 'HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: implications for therapy and vaccine development,' is the subject of a report. "Our overall goal is to understand how viral envelope proteins mediate membrane fusion and pathogenesis. Membrane fusion is a crucial step in the delivery of the viral genome into the cell resulting in infection," scientists in the United States report.

"On the other hand, fusion activity of viral envelope glycoproteins expressed in infected cells may cause the demise of uninfected bystander cells by apoptosis. Our general approach is to kinetically resolve steps in the pathway of viral envelope glycoprotein-mediated...

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