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HIV/AIDS Vaccines
Reports outline HIV/AIDS vaccines study results from Karolinska Institut
August 6th, 2008
New investigation results, 'B cell immunopathology during HIV-1 infection: lessons to learn for HIV-1 vaccine design,' are detailed in a study published in Vaccine. "Induction of broad HIV-1 neutralizing antibodies should be a major goal of an effective HIV-1 vaccine. However, B cells are severely damaged during HIV-1 infection with loss of memory B cells and decline of serological memory," scientists in Stockholm, Sweden report. "The molecular events leading to B cell damage must be further characterized with the aim of selecting vaccine components allowing preservation of B cell functions. This review focuses on B cell damage and antibody responses in...
Source: Vaccine Weekly (2008-08-06)
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