Influenza

Reports from Erasmus University add new data to research in influenza

Published in Vaccine Weekly, August 13th, 2008

"Since the number of human cases of infection with avian H5N1 influenza viruses is ever increasing, a pandemic outbreak caused by these viruses is feared. Therefore, in addition to virus-specific antibodies, there is considerable interest in immune correlates of protection against these viruses, which could be a target for the development of more universal vaccines," investigators in Netherlands report.

"After infection with seasonal influenza A viruses of the H3N2 and H1N1 subtypes, individuals develop virus-specific cytotoxic T-lymphocyte responses, which are mainly directed against the relatively conserved internal proteins of the virus, like the nucleoprotein (NP)....

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Source: Vaccine Weekly (2008-08-13)

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