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Immunization
Researchers at Children's Hospital target immunization
August 13th, 2008
Researchers detail in 'Bactericidal antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed factor H-binding protein and genetically attenuated endotoxin,' new data in immunization. "Outer membrane vesicle (OMV) vaccines from mutant Neisseria meningitidis strains engineered to overexpress factor H-binding protein (fHbp) have elicited broadly protective serum antibody responses in mice. The vaccines investigated were not treated with detergents to avoid extracting fHbp, which is a lipoprotein," researchers in the United States report. "Because of their high endotoxin content, the vaccines would not be safe to administer to...
Source: Vaccine Weekly (2008-08-13)
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