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Virology
Study data from Erasmus Medical Center, Department of Virology update knowledge of virology
August 13th, 2008
New research, 'Generation of temperature-sensitive human metapneumovirus strains that provide protective immunity in hamsters,' is the subject of a report. "Human metapneumovirus (HMPV) causes acute respiratory tract illness primarily in young children, immunocompromised individuals and the elderly. Vaccines would be desirable to prevent severe illnesses in these risk groups," scientists in Rotterdam, Netherlands report. "Here, we describe the generation and evaluation of cold-passage (cp) temperature-sensitive (ts) HMPV strains as vaccine candidates. Repeated passage of HMPV at low temperatures in Vero cells resulted in the accumulation of mutations in the viral...
Source: Vaccine Weekly (2008-08-13)
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