Human Papillomavirus
Studies by S.J. Liao and co-authors describe new findings in human papillomavirus
Published in Vaccine Weekly, August 13th, 2008
According to recent research from Wuhan, People's Republic of China, "This study aimed to generate human papillomavirus (HPV) type 18 L1 virus-like particles (VLPs) and investigated the immunity effectiveness in vitro by using the Bac to Bac baculovirus expression system and Ni-NTA purification system to express and purify the VLP. The bio-function and immune response of purified VLP were analyzed by a mouse erythrocyte haemagglutination assay and the IFN-gamma ELISPOT."
"The proteins of interest, primarily located at the nucleus, formed VLP by self-assembly, and had an effective immune activity in vitro. The level of IFN-gamma in the specific HPV18 positive group was...
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Source: Vaccine Weekly (2008-08-13)
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