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Vaccine Weekly

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Immunization



New immunization data have been reported by S.A. Roiko and co-authors



August 13th, 2008

According to recent research from the United States, "Vaccination against nicotine reduces the behavioral effects of nicotine in rats, and it is under clinical evaluation as a treatment for tobacco addiction. Efficacy is limited by the need for high serum nicotine-specific antibody (NicAb) levels, and currently available nicotine vaccines do not uniformly generate the required NicAb levels."

"Passive immunization with a nicotine-specific monoclonal antibody (Nic311) has also shown efficacy in rats. The principal aim of this study was to determine whether the combined use of vaccination and passive immunization would produce greater effects than vaccination alone on...


Source: Vaccine Weekly (2008-08-13)

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