Influenza

Study findings from P.O. Ilyinskii et al provide new insights into influenza

Published in Vaccine Weekly, August 20th, 2008

"It is assumed that the proteosome-processing characteristics of fusion constructs can be predicted from the sum of the proteosome sensitivity of their components. In the present study, we observed that a fusion construct consisting of proteosome-degradable proteins does not necessarily result in a proteosome-degradable chimera," investigators in the United States report.

"Conversely, fusion of proteosome-resistant proteins may result in a proteosome-degradable composite. We previously demonstrated that conserved influenza proteins can be unified into a single fusion antigen that is protective, and that vaccination with combinations of proteosome-resistant and...

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Source: Vaccine Weekly (2008-08-20)

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