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Immunology
New immunology study results reported from Queensland Institute of Medical Research
August 20th, 2008
Current study results from the report, 'Generating functional CD8+ T cell memory response under transient CD4+ T cell deficiency: implications for vaccination of immunocompromised individuals,' have been published. "Studies based on either MHC class II-knockout or CD4+ T cell-depleted murine models have demonstrated a critical role for CD4+ T cells in the generation of CD8+ T cell memory. However, it is difficult to extend these findings to immunocompromised humans where a complete loss of CD4+ T cells is rarely observed," scientists in Brisbane, Australia report. "Here, we have developed a model setting, which allows studies on the generation of CD8+ T cell memory...
Source: Vaccine Weekly (2008-08-20)
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