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Hepatitis C Virus
Studies from Fourth Military Medical University yield new information about hepatitis C virus
August 20th, 2008
According to recent research from Xian, People's Republic of China, "Hepatitis C virus (HCV) is a major cause of liver disease worldwide. HCV infection is associated with high morbidity and has become a major problem in public health." "Until now, there has been no effective prophylactic or therapeutic vaccine. BCG, a live vaccine typically used for tuberculosis prevention, has been increasingly utilized as a vector for the expression of recombinant proteins that will induce specific humoral and cellular immune responses. In this study, recombinant BCG (rBCG) was engineered to express a HCV multi-epitope antigen CtEm, and HLA-A2.1 transgenic mice were immunized with...
Source: Vaccine Weekly (2008-08-20)
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