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Strep Infection
New strep infection research from Harvard University discussed
August 20th, 2008
According to a study from the United States, "CD4(+) T-cell-dependent acquired immunity confers antibody-independent protection against pneumococcal colonization. Since this mechanism is poorly, understood for extracellular bacteria, we assessed the antigen specificity of the induction and recall of this immune response by using BALB/c DO11.10Rag(-/-) mice, which lack mature B and T cells except for CD4(+) T cells specific for the OVA(323-339) peptide derived from ovalbumin." "Serotype 613 Streptococcus pneumoniae strain 603S and unencapsulated strain Rx1 Delta lytA were modified to express OVA(323-339) as a fusion protein with surface protein A (PspA) (strains...
Source: Vaccine Weekly (2008-08-20)
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