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Cancer Vaccines
Data on cancer vaccines described by investigators at University of Lausanne, Ludwig Institute for Cancer Research
August 20th, 2008
Investigators publish new data in the report 'Lentivector immunization induces tumor antigen-specific B and T cell responses in vivo.' "Expression of the cancer/germ-line antigen NY-ESO-1 by tumors elicits spontaneous humoral and cellular immune responses in some cancer patients. Development of vaccines capable of stimulating such comprehensive immune responses is desirable," scientists in Epalinges, Switzerland report. "We have produced recombinant lentivectors directing the intracellular synthesis of NY-ESO-1 (rLV/ESO) and have analyzed the in vivo immune response elicited by this vector. Single injection of rLV/ESO into HLA-A2-transgenic mice elicited long-lasting B...
Source: Vaccine Weekly (2008-08-20)
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