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Immunization
Report summarizes immunization study findings from T. Aebischer and co-researchers
August 27th, 2008
According to recent research published in the journal Gut, "Helicobacter pylori remains a global health hazard, and vaccination would be ideal for its control. Natural infection appears not to induce protective immunity." "Thus, the feasibility of a vaccine for humans is doubtful. In two prospective, randomised, double-blind, controlled studies (Paul Ehrlich Institute application nos 0802/02 and 1097/01), live vaccines against H pylori were tested in human volunteers seronegative for, and without evidence of, active H pylori infection. Volunteers (n = 58) were immunised orally with Salmonella enterica serovar Typhi Ty21a expressing H pylori urease or HP0231, or...
Source: Vaccine Weekly (2008-08-27)
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