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Transplantation
Study results from China University update understanding of transplantation
August 27th, 2008
According to recent research published in the journal Transplantation Proceedings, "Previous studies have shown that vaccinating rodents with anti-donor-specific T cells significantly prolonged allograft survival; however, the putative mechanism of the tolerance remains unclear. In this study, we used the model of heterotopic heart transplantation between the C57BL/6 donor mice and BALB/c recipient mice vaccinated with anti-donor (C57BL/6) or anti-third party (C3H)-specific T cells to determine whether T cells prolong survival of mouse heart allografts and which cells were involved in induction of allograft tolerance." "We observed that the mean survival time...
Source: Vaccine Weekly (2008-08-27)
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