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Vaccine Weekly

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Immunization



Reports outline immunization study results from Tzu Chi University, Department of Internal Medicine



August 27th, 2008

New investigation results, 'HLA and response to booster hepatitis B vaccination in anti-HBs-seronegative adolescents who had received primary infantile vaccination,' are detailed in a study published in Vaccine. "To explore contemporarily genetic and non-genetic determinants of long-term immunological memory to hepatitis B (HB) vaccination, we conducted a case-control study nested in an adolescent cohort of booster recipients who had received primary infantile HB vaccination but with residual anti-HBs titers <10 mIU/mL at 15-18 years of age. High-resolution phenotypes of human leukocyte antigen (HLA)-A, -B, and -DRB1 loci were determined by sequence-specific oligonucleotide probe...


Source: Vaccine Weekly (2008-08-27)

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