Immunology
New findings from P.J. van de Berg and co-authors describe advances in immunology
Published in Vaccine Weekly, August 27th, 2008
Investigators publish new data in the report 'Cytotoxic human CD4(+) T cells.' "The induction of adaptive immune responses critically depends on helper signals provided by CD4(+) T cells. These signals not only license antigen presenting cells (APC) to activate naïve CD8(+) T cells leading to the formation of vast numbers of cytotoxic T lymphocytes but also support the differentiation of B cells into immunoglobulin-secreting plasma cells," scientists in Amsterdam, Netherlands report.
"Next to these helper functions, a subpopulation of CD4(+) T cells can also directly function as effector cells by executing cytotoxicity in a peptide-specific and MHC class II-restricted...
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Source: Vaccine Weekly (2008-08-27)
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