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Vaccine Weekly

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Monoclonal Antibodies



Researchers from University of Massachusetts report on findings in monoclonal antibodies



August 27th, 2008

Fresh data on monoclonal antibodies are presented in the report 'Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A.' "Recent data suggest that Clostridium difficile-associated diarrhea is becoming more severe and difficult to treat. Antibody responses to C. difficile toxin A are protective against symptomatic disease and recurrence," investigators in the United States report.

"We examined the safety and pharmacokinetics (pk) of a novel neutralizing human monoclonal antibody against C. difficile toxin A (CDA1) in healthy adults....


Source: Vaccine Weekly (2008-08-27)

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