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Vaccines
Reports summarize vaccines research from P. Pasquali and co-authors
August 27th, 2008
Investigators publish new data in the report 'Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice.' "Salmonella enterica has long been recognised as an important zoonotic pathogen of economic significance, both in animals and humans. We have recently shown that inactivation of the ZnuABC high affinity zinc transporter significantly affects the pathogenicity of S. enterica, likely due to zinc shortage in the eukaryotic tissues," researchers in Rome, Italy report. "Here, we demonstrate that a S. enterica serovar Typhimurium znuABC deleted strain is able to induce a short...
Source: Vaccine Weekly (2008-08-27)
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