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Vaccine Weekly

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Whooping Cough Vaccines



New whooping cough vaccines research from R.C. Kohberger and colleagues discussed



August 27th, 2008

New research, 'Prediction of pertussis vaccine efficacy using a correlates of protection model,' is the subject of a report. According to a study from the United States, "A previously developed statistical model relates vaccine immune responses to protection against pertussis disease in a household contact setting. Before this model can be used to predict the risk of disease based on immune responses, it must be validated to demonstrate reliable predictions."

"The model is shown here to be validated in terms of statistical criteria (Prentice surrogacy measures) as well as predictive capability in an independent efficacy trial (meta-analysis). Additionally, the model is...


Source: Vaccine Weekly (2008-08-27)

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