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Vaccine Weekly

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Cholera



Research from Z.M. He and co-researchers in the area of cholera described



August 27th, 2008

"To assess the utility of the tomato fruit-specific E8 gene's promoter for driving vaccine antigen expression in plant, the 2.2 kb and 1.1 kb E8 promoters were isolated and sequenced from Lycopersicon esculentum cv. Jinfeng #1. The 1.1 kb promoter was fused to vaccine antigen HBsAg M gene for the transfer to Nicotiana tabacum, and the CaMV 35S promoter was used for comparison," scientists writing in the journal Genetica report.

"Cholera toxin B (ctb) gene under the control of the 1.1 kb promoter was transformed into both N. tabacum and L esculentum. Southern blot hybridization confirmed the stable integration of the target genes into the tomato and tobacco...


Source: Vaccine Weekly (2008-08-27)

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