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Vaccine Weekly

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HIV/AIDS



New HIV/AIDS study findings recently were reported by researchers at University of Alabama



August 27th, 2008

According to a study from the United States, "The precise identification of the HIV-1 envelope glycoprotein (Env) responsible for productive clinical infection could be instrumental in elucidating the molecular basis of HIV-1 transmission and in designing effective vaccines. Here, we developed a mathematical model of random viral evolution and, together with phylogenetic tree construction, used it to analyze 3,449 complete env sequences derived by single genome amplification from 102 subjects with acute HIV-1 (clade B) infection."

"Viral env genes evolving from individual transmitted or founder viruses generally exhibited a Poisson distribution of mutations and...


Source: Vaccine Weekly (2008-08-27)

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