Gene Therapy

Researchers from Michigan State University report recent findings in gene therapy

Published in Vaccine Weekly, August 27th, 2008

According to recent research from the United States, "Alternative human and non-human Ad serotype vectors are currently studied for gene therapy and/or vaccine applications to capitalize upon their likely ability to avoid pre-existing immunity to HAd5. However, relatively little attention has been given to the nature and scope of innate immune responses generated by alternative Ad serotypes."

"In this study, we characterized several innate immune responses after intravenous administration of wild-type Ad serotypes HAd31, HAd3, HAd5, HAd37, SAd23 and HAd41, representing groups A-F, respectively. Notably, biodistribution studies revealed significant differences between...

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Source: Vaccine Weekly (2008-08-27)

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