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Hepatitis B Virus Vaccines
New hepatitis B virus vaccines research from Fudan University outlined
September 3rd, 2008
Investigators publish new data in the report 'Immunogenicity of recombinant hepatitis B virus surface antigen fused with preS1 epitopes expressed in rice seeds.' "To test the possibility of producing a novel hepatitis B vaccine in plants, the modified hepatitis B virus (HBV) surface antigen (HBsAg) gene SS1 was expressed in rice under the control of the seed-specific Glub-4 promoter. The SS1 gene encodes a fusion protein consisting of amino acids 21-47 of the hepatocyte receptor-binding presurface 1 region (preS1) fused to the truncated C-terminus of the major HBV surface (S) protein," scientists in Shanghai, People's Republic of China report. "The production of...
Source: Vaccine Weekly (2008-09-03)
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