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Vaccine Weekly

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Immunization



Researchers at Center for Biologics Evaluation and Research target immunization



September 3rd, 2008

Researchers detail in 'Antibody induced by immunization with the Jeryl Lynn mumps vaccine strain effectively neutralizes a heterologous wild-type mumps virus associated with a large outbreak,' new data in immunization. "Recent mumps outbreaks in older vaccinated populations were caused primarily by genotype G viruses, which are phylogenetically distinct from the genotype A vaccine strains used in the countries affected by the outbreaks. This finding suggests that genotype A vaccine strains could have reduced efficacy against heterologous mumps viruses," researchers in the United States report.

"The remote history of vaccination also suggests that waning immunity could...


Source: Vaccine Weekly (2008-09-03)

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