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Vaccine Weekly

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Myeloma Therapy



Research from Vanderbilt University, Department of Pediatrics in myeloma therapy provides new insights



September 3rd, 2008

New research, 'An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies,' is the subject of a report. According to a study from the United States, "We sought to develop and optimize a hybridoma-based technology for generating human hybridomas that secrete virus-specific monoclonal antibodies for clinical diagnosis and therapy. We developed a novel electrofusion protocol for efficiently fusing Epstein-Barr virus (EBV)-transformed human B cells with myeloma partners."

"We tested seven myeloma cell lines and achieved highest efficiency when the HMMA 2.5 line was used. We optimized the electrofusion process by improving cell...


Source: Vaccine Weekly (2008-09-03)

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