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DNA Vaccines

Reports summarize DNA vaccines research from University of Sao Paulo

Published in Vaccine Weekly, September 3rd, 2008

According to a study from Sao Paulo, Brazil, "Aiming to evaluate some parameters to influence the immune response to DNA vaccination, we compare three protocols of DNA immunization (i.m. injections, i.m. injections followed by electroporation, and the effect of i.p. injection of stably antigen-transfected cells before DNA administration), using three different antigens."

"Statistical analyses showed that electroporation after intramuscular injections provided an immune response comparable to that obtained by pre-treatment with antigen-transfected cells and similar to that obtained by protein immunization," wrote C.B. Parise and colleagues, University of Sao...

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