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Vaccine Weekly

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Kidney Disease



Study data from A.B. Hauser and colleagues update understanding of kidney disease



September 10th, 2008

According to a study from Curitiba, Brazil, "From the immunologic viewpoint, chronic kidney disease (CKD) is characterized by disorders of both the innate and adaptive systems, generating a complex and still not fully understood immune dysfunction. Markers of a chronically activated immune system are closely linked to several complications of CKD and represent powerful predictors for mortality in the CKD population."

"On the other hand, CKD patients respond poorly to vaccination and to challenges such as bacterial infection. Interestingly, the main causes of death in patients with CKD are cardiovascular and infectious diseases, both being pathologic processes closely...


Source: Vaccine Weekly (2008-09-10)

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