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Vaccine Weekly

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DNA Research



Research conducted at Tokyo University has provided new information about DNA research



September 10th, 2008

Data detailed in 'Effects of menstrual cycle on gene transfection through mouse vagina for DNA vaccine' have been presented. According to recent research published in the International Journal of Pharmaceutics, "Human immunodeficiency virus (HIV) infections mainly occur through the vaginal and rectal mucosal membranes. In the present study, to develop a DNA vaginal vaccine against viral and bacterial infections, the effects of the menstrual cycle on DNA transfection through the vaginal mucosa in female mice and transfection enhancement by electroporation, a chelating agent, cell-penetrating peptides (CPP) and nuclear localizing signals (NLS) were investigated."

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Source: Vaccine Weekly (2008-09-10)

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