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Severe Acute Respiratory Syndrome
Researchers at Tsinghua University, Chinese Academy of Medical Sciences publish new data on severe acute respiratory syndrome
September 10th, 2008
New research, 'Endocytosis of the receptor-binding domain of SARS-CoV spike protein together with virus receptor ACE2,' is the subject of a report. According to a study from Beijing, People's Republic of China, "Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. Amino acids 319-510 on the S protein have been mapped as the receptor-binding domain (RBD), which mediates binding to the SARS-CoV receptor angiotensin converting enzyme 2 (ACE2) on SARS-CoV susceptible cells." "In this study, we expressed a fusion protein containing the human codon-optimized RBD of the SARS-CoV spike protein linked to the Fc...
Source: Vaccine Weekly (2008-09-10)
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