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Encephalitis
Research from D.L. Fine and co-researchers in the area of encephalitis described
September 10th, 2008
"Assessment of neurovirulence is a standard test for vaccines derived from virulent neurotropic viruses. This study evaluated the potential neurovirulence ofV3526, a live attenuated vaccine derived from a fulllength infectious clone of Venezuelan equine encephalitis virus (VEEV) Trinidad donkey strain (TrD), a comparator VEEV vaccine (TC-83), TrD, and process control material (PCM) in juvenile rhesus macaques," scientists writing in the journal Vaccine report. "Following intrathalamic/intraspinal (IT/IS) or subcutaneous (SC) inoculations, animals were observed for periods of 18, 91 or 181 days for paresis, paralysis, neurological disorders and other signs...
Source: Vaccine Weekly (2008-09-10)
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