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Vaccine Weekly

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Foot and Mouth Disease



Reports outline foot and mouth disease research from S. Parida and colleagues



September 10th, 2008

"This study has quantified the level of foot-and-mouth disease virus (FMDV) replication and shedding in vaccinated sheep and correlated this to the severity of clinical signs, the induction of antibodies against FMDV non-structural proteins (NSPs) and the transmission of virus to in-contact vaccinated sentinel sheep. To mimic an emergency vaccination regime in the field, sheep were vaccinated with 01 Manisa vaccine and 4 or 10 days later were indirectly challenged with aerosols from 01 UKG FMDV infected pigs," researchers in Pirbright, the United Kingdom report.

"Vaccinated and control unvaccinated sheep were monitored for a minimum of 39 days post-challenge. The...


Source: Vaccine Weekly (2008-09-10)

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