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Vaccine Weekly

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Flu Vaccines



Study results from Intercell AG update understanding of flu vaccines



September 10th, 2008

"The compromised immune responses in the elderly as well as the threat of pandernic influenza necessitate the development of improved influenza vaccines. This study provides evidence that 1010, a two-component synthetic adjuvant signalling through TLR-9, augments humoral and cellular immune responses to seasonal influenza vaccines," scientists in Vienna, Austria report.

"Experiments performed in young adult mice showed increased HI titres and higher levels of IgG2a antibodies that were accompanied by the induction of IFN-,y producing CD4' T cells after single vaccination with reduced doses of vaccine antigens, even 200 days after single immunisation. Importantly,...


Source: Vaccine Weekly (2008-09-10)

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