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Vaccine Weekly

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Foot and Mouth Disease



Reports from M. Yang and colleagues advance knowledge in foot and mouth disease



September 10th, 2008

"A double antibody sandwich ELISA for quantification of foot-and-mouth disease (FMD) whole virus particle was developed using two monoclonal antibodies (mAbs) against FIVID virus (FMDV) serotype O and A. The antibody binding epitopes were characterized," scientists in Winnipeg, Canada report.

"The two mAbs reacted with all of the tested FMDV strains," wrote M. Yang and colleagues.

The researchers concluded: "The use of these two mAbs in the sandwich ELISA will allow the quantification of FMD whole virus particles during vaccine manufacture."

Yang and colleagues published their study in Vaccine (Production of monoclonal...


Source: Vaccine Weekly (2008-09-10)

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