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Vaccine Weekly

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Influenza



Researchers from Laval University provide details of new studies and findings in the area of influenza



September 10th, 2008

"With the emergence of highly virulent influenza viruses and the consequent risk of pandernics, new approaches to designing universal influenza vaccines are urgently needed. In this report, we demonstrate the potential of using a papaya mosaic virus (PapMV) platform carrying the universal M2e influenza epitope (PapMV-CP-M2e) as a candidate flu vaccine," scientists in Canada report.

"We show that PapMV-CP-M2e virus-like particles (VLPs) can induce production in mice of anti-M2e antibodies that can recognize influenza-infected cells. PapMVCP-M2e discs made of 20 coat protein (CP) subunits were shown to be poorly immunogenic compared to PapMV-CP-M2e VLPs composed of...


Source: Vaccine Weekly (2008-09-10)

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