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Gene Therapy
Catholic University of Korea publishes research in gene therapy
September 10th, 2008
Research findings, 'Efficient antitumor immunity in a murine colorectal cancer model induced by CEA RNA-electroporated B cells,' are discussed in a new report. According to a study from Seoul, Korea, "RNA electroporation as a gene delivery method is more feasible and safer as compared with viral vectors. RNA-loaded dendritic cells (DC) have been used to induce T cell responses against tumor rejection antigens and B cells can also act as antigen-presenting cells for cellular vaccines." "In this study, we compared B cells and DC, after electroporation with carcinoembryonic antigen (CEA) RNA, for their capacity to generate cytotoxic T lymphocytes and antitumor immunity....
Source: Vaccine Weekly (2008-09-10)
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