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Vaccine Weekly

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Sarcoma



Research on sarcoma detailed by scientists at Peking University



September 17th, 2008

According to a study from Beijing, People's Republic of China, "Given the effective immunotherapy of DC-based vaccine in other cancers, we hypothesized DC-based vaccines would induce effective immune responses against Ewing's sarcoma. To verify this hypothesis and develop the most effective dendritic cell vaccine against Ewing's sarcoma, we evaluated the antitumor efficacy of dendritic cell-Ewing's sarcoma hybrids and dendritic cells pulsed with other antigen-loading methods, including cell lysates and the characteristic EWS-FLI1 gene of Ewing's sarcoma, using an A673 cell line as a model."

"The hybrids were generated by electrofusion with fusion efficiency and...


Source: Vaccine Weekly (2008-09-17)

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