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DNA Vaccines
Studies from University of Sao Paulo, Biomedical Sciences Institute in the area of DNA vaccines described
September 17th, 2008
Investigators publish new data in the report 'Boosting systemic and secreted antibody responses in mice orally immunized with recombinant Bacillus subtilis strains following parenteral priming with a DNA vaccine encoding the enterotoxigenic Escherichia coli (ETEC) CFA/I fimbriae B subunit.' According to a study from Sao Paulo, Brazil, "Recombinant Bacillus subtilis strains, either spores or vegetative cells, may be employed as safe and low cost orally delivered live vaccine vehicles. In this study, we report the use of an orally delivered B. subtilis vaccine strain to boost systemic and secreted antibody responses in mice i.m. primed with a DNA vaccine encoding the structural subunit...
Source: Vaccine Weekly (2008-09-17)
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