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Vaccine Weekly

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Filariasis Vaccines



Reports outline filariasis vaccines study findings from Banaras Hindu University, Department of Biochemistry



September 17th, 2008

Scientists discuss in 'Filarial glutathione-S-transferase: a potential vaccine candidate against lymphatic filariasis' new findings in filariasis. "Present report enumerates the vaccine potential of a glutathione-S-transferase purified from Setaria cervi against lymphatic filariasis. In jirds (Meriones unguiculatus) vaccination trial, a very significant 82.75% (p <0.005) reduction in adult parasite burden was observed in ScGST immunized group after 90 days post Brugia malayi L3 challenge," researchers in Varanasi, India report.

"An inverse correlation between the antibody level and worm burden was found in ScGST immunized group (Person's correlation r=0.943,...


Source: Vaccine Weekly (2008-09-17)

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