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Vaccine Weekly

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Vaccines



Findings in vaccines reported from Academy of Military Medical Science



September 17th, 2008

Fresh data on vaccines are presented in the report 'Enhancement by IL-18 of the protective effect of a Schistosoma japonicum 26kDa GST plasmid DNA vaccine in mice.' According to recent research from Changchun, People's Republic of China, "Two recombinant plasmids pVAX/Sj26GST and pVAX/mIL-18 containing Schistosoma japonicum 26kDa GST and murine IL-18 were evaluated for their ability to protect mice against S. japonicum challenge. Mice were given 2 intramuscular immunizations 3 weeks apart, and challenged with S. japonicum cercariae 4 weeks later."

"Adult worm and egg burdens were determined 48 days post-challenge. All animals vaccinated with...


Source: Vaccine Weekly (2008-09-17)

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