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Vaccine Weekly

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HIV/AIDS



Reports on HIV/AIDS findings from University of Alabama provide new insights



September 17th, 2008

According to recent research published in the Journal of Virology, "A phase 1 clinical vaccine study of a human immunodeficiency virus type 1 (HIV-1) vaccine regimen comprising a DNA prime formulation (5-valent env and monovalent gag) followed by a 5-valent Env protein boost for seronegative adults was previously shown to induce HIV-1-specific T cells and anti-Env antibodies capable of neutralizing cross-clade viral isolates. In light of these initial findings, we sought to more fully characterize the HIV-1-specific T cells by using polychromatic How cytometry."

"Three groups of participants were vaccinated three times with 1.2 mg of DNA administered...


Source: Vaccine Weekly (2008-09-17)

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