Influenza

New findings from J. Stech and co-authors in the area of influenza published

Published in Vaccine Weekly, September 17th, 2008

According to recent research published in the journal Expert Review of Vaccines, "Influenza A viruses are a public-health concern as they cause annual epidemics and may initiate a pandemic. Common inactivated influenza A vaccines induce a serum antibody response, which may not be protective against virus variation in the field."

"In contrast to conventional vaccines, the intranasally administered live influenza vaccine may have the potential to induce long-lived and heterosubtypic immunity. In this perspective, attenuated hemagglutinin cleavage-site mutants are discussed in view of usage as influenza live vaccines. This approach allows the convertion of any...

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Source: Vaccine Weekly (2008-09-17)

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