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Chlamydia Immunology



Data on chlamydia immunology discussed by researchers at Statens Serum Institute



September 17th, 2008

A report, 'Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model,' is newly published data in The Journal of Infectious Diseases. According to a study from Copenhagen, Denmark, "Immunity to chlamydia is thought to rely on interferon (IFN)-gamma-secreting T helper cells type 1 (Th1) with an additional effect of secreted antibodies. A need for Th1-polarizing adjuvants in experimental chlamydia vaccines has been demonstrated, and antigen conformation has also been reported as being important for raising protective immunity."

"C57BL/6 mice vaccinated with native...


Source: Vaccine Weekly (2008-09-17)

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