Malaria

Research from E.S. Bergmannleitner et al broadens understanding of malaria

Published in Vaccine Weekly, September 24th, 2008

According to recent research published in the Malaria Journal, "Antibodies are the main effectors against malaria blood-stage parasites. Evaluation of functional activities in immune sera from Phase 2a/b vaccine trials may provide invaluable information in the search for immune correlates of protection."

"However, the presence of antimalarial-drugs, improper collection/storage conditions or concomitant immune responses against other pathogens can contribute to non-specific anti-parasite activities when the sera/plasma are tested in vitro. Purification of immunoglobulin is a standard approach for reducing such non-specific background activities, but the...

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Source: Vaccine Weekly (2008-09-24)

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