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Malaria
Research in the area of malaria reported from A. Vaughan and colleagues
September 24th, 2008
According to recent research published in the journal Bioinformatics, "The sequencing of the Plasmodium yoelii genome, a model rodent malaria parasite, has greatly facilitated research for the development of new drug and vaccine candidates against malaria. Unfortunately, only preliminary gene models were annotated on the partially sequenced genome, mostly by in silico gene prediction, and there has been no major improvement of the annotation since 2002." "Here we report on a systematic assessment of the accuracy of the genome annotation based on a detailed analysis of a comprehensive set of cDNA sequences and proteomics data. We found that the coverage of the...
Source: Vaccine Weekly (2008-09-24)
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